منابع مشابه
Women's Skin throughout Lifetime
1 Laboratory of Skin Bioengineering and Imaging (LABIC), Department of Clinical Sciences, Liège University, 4000 Liège, Belgium 2Department of Clinical Toxicology, University Hospital of Liège, 4000 Liège, Belgium 3Department of Pathology, Unilab Lg, University Hospital of Liège, 4000 Liège, Belgium 4Department of Dermatology, University Hospital Saint-Jacques, 25030 Besançon, France 5 Inserm U...
متن کاملCognition in the adult with childhood-onset GH deficiency.
The GH/IGF1 axis may play an important role in cognitive function. This theory is supported by the finding that both GH and IGF1 receptors are located in several brain areas such as the hippocampus, a brain area that is known to play an essential role in cognitive processes, especially memory and learning. However, the exact mechanism by which the GH/IGF1 axis influences the cognitive functions...
متن کاملImpact of Growth Hormone (GH) Deficiency and GH Replacement upon Thymus Function in Adult Patients
BACKGROUND Despite age-related adipose involution, T cell generation in the thymus (thymopoiesis) is maintained beyond puberty in adults. In rodents, growth hormone (GH), insulin-like growth factor-1 (IGF-1), and GH secretagogues reverse age-related changes in thymus cytoarchitecture and increase thymopoiesis. GH administration also enhances thymic mass and function in HIV-infected patients. Un...
متن کاملImpact of GH replacement therapy on sleep in adult patients with GH deficiency of pituitary origin.
OBJECTIVES We previously reported that adult patients with GH deficiency (GHD) due to a confirmed or likely pituitary defect, compared with healthy controls individually matched for age, gender, and BMI, have more slow-wave sleep (SWS) and higher delta activity (a marker of SWS intensity). Here, we examined the impact of recombinant human GH (rhGH) therapy, compared with placebo, on objective s...
متن کاملWhich patients do not require a GH stimulation test for the diagnosis of adult GH deficiency?
Adult GH deficiency (GHD) is currently diagnosed in patients with either a history of childhood-onset GHD or acquired hypothalamic-pituitary disease by GH stimulation testing. However, GH stimulation tests are invasive, time consuming, and associated with side effects. Based on preliminary analyses of patients enrolled in the U.S. Hypopituitary Control and Complications Study (HypoCCS), we prop...
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ژورنال
عنوان ژورنال: European Journal of Endocrinology
سال: 2009
ISSN: 0804-4643,1479-683X
DOI: 10.1530/eje-09-0258